A New Indole Derivative, LWX-473, Overcomes Glucocorticoid Resistance in Jurkat Cells by Activating Mediators of Apoptosis

Background: Glucocorticoids (GCs) are commonly used as the primary chemotherapy for lymphoid malignancies, including acute lymphoblastic leukemia (ALL).However, the development of GC resistance limits their prolonged use.Methods: In this study, we investigated the potential of a newly synthesized indole derivative called LWX-473, in combination wit

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Esophageal disorders in patients with irritable bowel syndrome

Aim.To study the whole range of esophageal disorders in patients with irritable bowel syndrome (IBS) using high-tech methods.Materials and methods.102 IBS patients (47 males, mean age 40.8, diagnosis of IBS was established according to Rome III criteria) with esophageal symptoms (heartburn, belching, globus sensation and noncardiac chest pain) were

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On Maximum Entropy and Inference

Maximum entropy is a powerful concept that entails a sharp separation between relevant and irrelevant variables.It is typically invoked in inference, once an assumption is made on what the relevant variables are, in order to estimate a model from data, that affords predictions on all other (dependent) wild turkey camp nelson variables.Conversely, m

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An encryption algorithm for multiple medical images based on a novel chaotic system and an odd-even separation strategy

Abstract The continuous evolution of information technology underscores the growing emphasis on data security.In the realm of medical imaging, various diagnostic images represent the privacy of individuals, and the potential repercussions of their unauthorized disclosure are substantial.Therefore, this study introduces a novel chaotic system (TLCMC

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